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1 / 10 photos



$1,750,000
Active37 21st Avenue, Isle of Palms SC 29451
Isle of Palms, SC 29451View on map
Est. $9,305/mo with 20% down at 6.99%
MLS #26014448
Potential Cost Advantage with Nestor
$43,750
Based on $1,750,000 and a typical 2.5%–3.0% buyer-side compensation. Actual savings vary.
No buyer agent commission requested
You pay a flat $599 fee to Nestor when your offer is accepted — that's it.
★ Why Nestor flags this home
Quick facts
About this home
Rare opportunity to build on a corner lot in the heart of Isle of Palms. Located at the corner of 21st Avenue and Waterway Boulevard, this approximately 0.28-acre homesite offers potential sneak peeks of the Intracoastal Waterway along with beautiful grand oak trees that create a classic Lowcountry setting. Ideally located within walking distance to the beach, local restaurants, and island shops, this property offers the perfect blend of convenience and coastal living. Just moments from County Park beach access, the location provides easy access to everything that makes island life so desirable.The property currently has an existing home on site that would likely need to be removed, creating the opportunity to design and build your ideal island home. An arborist has reviewed theproperty, allowing potential for a larger footprint and future 2-story construction. Zoned SR-1, the lot contains approximately 12,196.8 square feet. As a corner lot, the property benefits from two front setbacks and two side setbacks: " Front Setbacks: 24' " Side Setbacks: 10' The existing home is currently used as a vacation rental, offering potential interim rental income while future plans are developed. All building plans, improvements, and permitting would be subject to approval by the Town of Isle of Palms. Known for its pristine beaches, relaxed Lowcountry charm, and endless outdoor recreation, Isle of Palms is one of the Charleston area's premier coastal communities. Enjoy nearby golf, boating, watersports, dining, and entertainment, making this an exceptional opportunity for a primary residence, vacation retreat, or investment property.
Property details
How buying works with Nestor
Get Nestor Certified
Complete identity verification to meet the requirements for requesting showings through Nestor.
Schedule your tour
Request showings through Nestor. NovaCasa coordinates the appointment and notifies you when it is confirmed.
Make your offer
Nestor helps you build a strong, competitive offer based on comps and market data.
Nestor tracks to closing
We manage deadlines, inspections, and keep you on track to close.
Listing information deemed reliable but not guaranteed. © 2026 Nestor. All rights reserved.
$1,750,000
37 21st Avenue, Isle of Palms SC 29451
Isle of Palms, SC 29451
Potential Cost Advantage
$43,750
Est. 2.5–3% buyer-side savings vs. traditional agent. Flat $599 Nestor fee applies.
HOUSING
OPPTY
Equal Housing Opportunity. All real estate listings are provided without regard to race, color, national origin, religion, sex, familial status, disability, or any other protected class. Listing data is deemed reliable but not guaranteed. Nestor and Novacasa LLC are committed to full compliance with all applicable fair housing laws. MLS data is provided for informational purposes only and does not constitute an offer or solicitation.